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TargetHypoxia-inducible factor (HIF-PH2)
LigandBDBM123018
Substrate/Competitorn/a
Meas. Tech.Enzyme Assay
IC50 150±n/a nM
Citation Kang, XLong, WMa, CWang, YCao, HWang, YTan, FHu, Y Compounds as hypoxia mimetics, and compositions and uses thereof US Patent US8742138 Publication Date 6/3/2014
More Info.:Get all data from this article,  Assay Method
 
Hypoxia-inducible factor (HIF-PH2)
Name:Hypoxia-inducible factor (HIF-PH2)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:36098.74
Organism:Rattus norvegicus (Rat)
Description:P59722
Residue:338
Sequence:
PRAQPAPAQPRVAPPPGGAPGAARAGGAARRGDSSTAASRVPGPEDATQAGSGPGPAEPS
SEDPPPSRSPGPERASLCPAGGGPGEALSPSGGLRPNGQTKPLPALKLALEYIVPCMNKH
GICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPG
CETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVT
CIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYA
ITVWYFDADERARAKVKYLTGEKGVRVELKPNSVSKDV
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  Blast E-value cutoff:
BDBM123018
NameBDBM123018
Synonyms:US8742138, 3
TypeSmall organic molecule
Emp. Form.C18H12ClNO6
Mol. Mass.373.744
SMILESOC(=O)CNC(=O)c1c2cc(ccc2c(O)oc1=O)-c1cccc(Cl)c1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a