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Target
Egl nine homolog 1
Ligand
BDBM123039
Substrate
n/a
Meas. Tech.
Enzyme Assay
Temperature
298.15±n/a K
IC50
30±n/a nM
Comments
extracted
Citation
 Kang, X; Long, W; Ma, C; Wang, Y; Cao, H; Wang, Y; Tan, F; Hu, Y Compounds as hypoxia mimetics, and compositions and uses thereof US Patent  US8742138 Publication Date 6/3/2014 
Target
Name:
Egl nine homolog 1
Synonyms:
EGLN1_RAT | Egln1 | Hypoxia-inducible factor (HIF-PH2)
Type:
Enzyme
Mol. Mass.:
36098.74
Organism:
Rattus norvegicus (Rat)
Description:
P59722
Residue:
338
Sequence:
PRAQPAPAQPRVAPPPGGAPGAARAGGAARRGDSSTAASRVPGPEDATQAGSGPGPAEPSSEDPPPSRSPGPERASLCPAGGGPGEALSPSGGLRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGRETGQQIGDEVRALHDTGKFTDGQLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCSGKLGNYRINGRTKAMVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEPKFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELKPNSVSKDV
  
Inhibitor
Name:
BDBM123039
Synonyms:
US8742138, 24
Type:
Small organic molecule
Emp. Form.:
C18H11Cl2NO6
Mol. Mass.:
408.189
SMILES:
OC(=O)CNC(=O)c1c2c(cccc2c(O)oc1=O)-c1ccc(Cl)c(Cl)c1
Structure:
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