Reaction Details Report a problem with these data
Target
G-protein coupled receptor 4
Ligand
BDBM123482
Substrate
n/a
Meas. Tech.
Radio Ligand Binding Assay
pH
8±n/a
IC50
34±n/a nM
Citation
 Miltz, W; Oberhauser, B; Vaupel, A; Velcicky, J; Weigand, K; Leleti, RR; Liu, Y; Du, Z Pyrazolo pyrimidine derivatives US Patent  US8748435 Publication Date 6/10/2014 
Target
Name:
G-protein coupled receptor 4
Synonyms:
G-protein coupled receptor 4 | G-protein coupled receptor 4 (GPR4) | GPR4 | GPR4_HUMAN
Type:
Enzyme
Mol. Mass.:
40994.40
Organism:
Homo sapiens (Human)
Description:
P46093
Residue:
362
Sequence:
MGNHTWEGCHVDSRVDHLFPPSLYIFVIGVGLPTNCLALWAAYRQVQQRNELGVYLMNLSIADLLYICTLPLWVDYFLHHDNWIHGPGSCKLFGFIFYTNIYISIAFLCCISVDRYLAVAHPLRFARLRRVKTAVAVSSVVWATELGANSAPLFHDELFRDRYNHTFCFEKFPMEGWVAWMNLYRVFVGFLFPWALMLLSYRGILRAVRGSVSTERQEKAKIKRLALSLIAIVLVCFAPYHVLLLSRSAIYLGRPWDCGFEERVFSAYHSSLAFTSLNCVADPILYCLVNEGARSDVAKALHNLLRFLASDKPQEMANASLTLETPLTSKRNSTAKAMTGSWAATPPSQGDQVQLKMLPPAQ
  
Inhibitor
Name:
BDBM123482
Synonyms:
US8748435, 7
Type:
Small organic molecule
Emp. Form.:
C33H45N5O4
Mol. Mass.:
575.7415
SMILES:
CCc1nn2c(C)cc(C)nc2c1Cc1ccc(\C=C\CC2(O)CCN(CC2)C(=O)CN(C)C(=O)OC(C)(C)C)cc1
Structure:
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