Reaction Details Report a problem with these data
Target
Calcitonin gene-related peptide 1
Ligand
BDBM126170
Substrate
n/a
Meas. Tech.
Binding Assay
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
0.77±n/a nM
Comments
extracted
Citation
 Stump, CA; Quigley, AG CGRP receptor antagonists US Patent  US8778957 Publication Date 7/15/2014 
Target
Name:
Calcitonin gene-related peptide 1
Synonyms:
CALC1 | CALCA | CALCA_HUMAN | CGRP | Calcitonin gene-related peptide (CGRP alpha) | Calcitonin gene-related peptide 1
Type:
Enzyme
Mol. Mass.:
13902.80
Organism:
Homo sapiens (Human)
Description:
P06881
Residue:
128
Sequence:
MGFQKFSPFLALSILVLLQAGSLHAAPFRSALESSPADPATLSEDEARLLLAALVQDYVQMKASELEQEQEREGSRIIAQKRACDTATCVTHRLAGLLSRSGGVVKNNFVPTNVGSKAFGRRRRDLQA
  
Inhibitor
Name:
BDBM126170
Synonyms:
US8778957, 3
Type:
Small organic molecule
Emp. Form.:
C32H31N5O2
Mol. Mass.:
517.6208
SMILES:
CC1(C)CN(Cc2ccc3cc4CC5(Cc4cc3n2)C(=O)Nc2ncccc52)[C@@H](Cc2ccccc2)C(=O)N1
Structure:
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