Reaction Details
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Report a problem with these dataTarget
Histamine H3 receptor
Ligand
BDBM50361016
Substrate
n/a
Meas. Tech.
Competition Binding Assay
pH
7.4±n/a
Temperature
277.15±n/a K
Ki
7.41±n/a nM
Comments
extracted
Citation
Black, LA; Gfesser, GA; Cowart, MD 4-substituted-2-amino-pyrimidine derivatives US Patent US8796297 Publication Date 8/5/2014 More Info.:
Target
Name:
Histamine H3 receptor
Synonyms:
HH3R | HRH3_RAT | Hrh3
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
48607.98
Organism:
Rattus norvegicus (rat)
Description:
n/a
Residue:
445
Sequence:
MERAPPDGLMNASGTLAGEAAAAGGARGFSAAWTAVLAALMALLIVATVLGNALVMLAFVADSSLRTQNNFFLLNLAISDFLVGAFCIPLYVPYVLTGRWTFGRGLCKLWLVVDYLLCASSVFNIVLISYDRFLSVTRAVSYRAQQGDTRRAVRKMALVWVLAFLLYGPAILSWEYLSGGSSIPEGHCYAEFFYNWYFLITASTLEFFTPFLSVTFFNLSIYLNIQRRTRLRLDGGREAGPEPPPDAQPSPPPAPPSCWGCWPKGHGEAMPLHRYGVGEAGPGVEAGEAALGGGSGGGAAASPTSSSGSSSRGTERPRSLKRGSKPSASSASLEKRMKMVSQSITQRFRLSRDKKVAKSLAIIVSIFGLCWAPYTLLMIIRAACHGRCIPDYWYETSFWLLWANSAVNPVLYPLCHYSFRRAFTKLLCPQKLKVQPHGSLEQCWK
Inhibitor
Name:
BDBM50361016
Synonyms:
CHEMBL501882 | US8796297, 13
Type:
Small organic molecule
Emp. Form.:
C9H15N5
Mol. Mass.:
193.2489
SMILES:
CN1CCN(CC1)c1ccnc(N)n1
Structure:
