Reaction Details Report a problem with these data
Target
Transthyretin
Ligand
BDBM128216
Substrate
n/a
Meas. Tech.
Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription
EC50
>167158±n/a nM
Citation
 PubChem, PC Luminescence-based cell-based high throughput dose response assay to identify activators of Transthyretin (TTR) transcription PubChem Bioassay (2014)[AID] 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM128216
Synonyms:
2-(4-biphenylyl)-N-(4-methylbenzyl)acetamide | MLS000576794 | N-(4-methylbenzyl)-2-(4-phenylphenyl)acetamide | N-[(4-methylphenyl)methyl]-2-(4-phenylphenyl)acetamide | N-[(4-methylphenyl)methyl]-2-(4-phenylphenyl)ethanamide | SMR000198074 | cid_2185046
Type:
Small organic molecule
Emp. Form.:
C22H21NO
Mol. Mass.:
315.4082
SMILES:
Cc1ccc(CNC(=O)Cc2ccc(cc2)-c2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: