Reaction Details Report a problem with these data
Target
Cannabinoid receptor 2
Ligand
BDBM135900
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Ki
0.9±n/a nM
Comments
extracted
Citation
 Carroll, WA; Dart, MJ; Frost, JM; Latshaw, SP; Kolasa, T; Li, T; Peddi, S; Liu, B; Perez-Medrano, A; Patel, M; Wang, X; Nelson, DW Compounds as cannabinoid receptor ligands US Patent  US8859596 Publication Date 10/14/2014 
Target
Name:
Cannabinoid receptor 2
Synonyms:
CANNABINOID CB2 | CB-2 | CB2 | CNR2_RAT | Cannabinoid CB2 receptor | Cannabinoid receptor | Cnr2 | rCB2
Type:
Enzyme
Mol. Mass.:
39366.68
Organism:
Rattus norvegicus (Rat)
Description:
Q9QZN9
Residue:
360
Sequence:
MAGCRELELTNGSNGGLEFNPMKEYMILSDAQQIAVAVLCTLMGLLSALENVAVLYLILSSQRLRRKPSYLFIGSLAGADFLASVIFACNFVIFHVFHGVDSRNIFLLKIGSVTMTFTASVGSLLLTAVDRYLCLCYPPTYKALVTRGRALVALGVMWVLSALISYLPLMGWTCCPSPCSELFPLIPNDYLLGWLLFIAILFSGIIYTYGYVLWKAHQHVASLAEHQDRQVPGIARMRLDVRLAKTLGLVMAVLLICWFPALALMGHSLVTTLSDKVKEAFAFCSMLCLVNSMINPIIYALRSGEIRSAAQHCLTGWKKYLQGLGSEGKEEAPKSSVTETEAEVKTTTGPGSRTPGCSNC
  
Inhibitor
Name:
BDBM135900
Synonyms:
US8859596, 188
Type:
Small organic molecule
Emp. Form.:
C22H28F3N5O2S
Mol. Mass.:
483.55
SMILES:
CCCCn1nc(s\c1=N/C(=O)c1cc(ccc1ON=C(N)C1CC1)C(F)(F)F)C(C)(C)C |w:19.20|
Structure:
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