Reaction Details Report a problem with these data
Target
5-hydroxytryptamine receptor 1B
Ligand
BDBM136319
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
Ki
37±n/a nM
Comments
extracted
Citation
 Andersson, J; Gyback, H; Johansson, A; Linde, CE; Malmstrom, J; Nordvall, G; Weigelt, T; Terp, G 2-carboxamide-7-piperazinyl-benzofuran derivatives US Patent  US8859534 Publication Date 10/14/2014 
Target
Name:
5-hydroxytryptamine receptor 1B
Synonyms:
5-HT1B | 5-hydroxytryptamine receptor 1A (5HT1B) | 5-hydroxytryptamine receptor 1B (5HT1B) | 5HT1B_CRIGR | HTR1B
Type:
Protein
Mol. Mass.:
42909.60
Organism:
Cricetulus griseus (Chinese hamster) (Cricetulus barabensis griseus)
Description:
P46636
Residue:
386
Sequence:
MEEQGIQCAPPPPAASQTGVPLVNLSHNCSAESHIYQDSIALPWKVLLVALLALITLATTLSNAFVIATVYRTRKLHTPANYLIASLAVTDLLVSILVMPVSTMYTVTGRWTLGQVVCDFWLSSDITCCTASIMHLCVIALDRYWAITDAVEYAAKRTPKRAAIMIALVWVFSISISLPPFFWRQAKAEEEVLTCLVNTDHVLYTVYSTGGAFYLPTLLLIALYGRIYVEARSRILKQTPNKTGKRLTRAQLITDSPGSTTSVTSINSRAPDLPSESGSPVYVNQVKVRVSDALLEKKKLMAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHMATLDFFNWLGYLNSLINPIIYTMSNEDFKQAFHKLIRFKCAG
  
Inhibitor
Name:
BDBM136319
Synonyms:
US8859534, 5
Type:
Small organic molecule
Emp. Form.:
C25H28N6O2
Mol. Mass.:
444.5288
SMILES:
Cn1cnc(CNC(=O)c2cc3cccc(N4CCN(CCc5ccccn5)CC4)c3o2)c1
Structure:
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