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Target
Transthyretin
Ligand
BDBM138366
Substrate
n/a
Meas. Tech.
FP Assay
IC50
1306±n/a nM
Citation
 Graef, IA; Alhamadsheh, M Identification of stabilizers of multimeric proteins US Patent  US8877795 Publication Date 11/4/2014 
Target
Name:
Transthyretin
Synonyms:
ATTR | PALB | Prealbumin | TBPA | TTHY_HUMAN | TTR | Transthyretin (TTR)
Type:
Enzyme
Mol. Mass.:
15884.31
Organism:
Homo sapiens (Human)
Description:
P02766
Residue:
147
Sequence:
MASHRLLLLCLAGLVFVSEAGPTGTGESKCPLMVKVLDAVRGSPAINVAVHVFRKAADDTWEPFASGKTSESGELHGLTTEEEFVEGIYKVEIDTKSYWKALGISPFHEHAEVVFTANDSGPRRYTIAALLSPYSYSTTAVVTNPKE
  
Inhibitor
Name:
BDBM138366
Synonyms:
US10278929, Compound 15 | US11337935, Compound 15 | US8877795, 15
Type:
Small organic molecule
Emp. Form.:
C16H16N6S
Mol. Mass.:
324.403
SMILES:
Cc1n[nH]c(C)c1CCc1nc2c3ccccc3[nH]c(=S)n2n1
Structure:
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