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TargetSphingosine 1-phosphate receptor 1 (S1P1)
LigandBDBM139213
Substrate/Competitorn/a
Meas. Tech.In Vitro Assay
Ki 3±n/a nM
Citation Montagne, CQuattropani, ASauer, WBombrun, A Oxadiazole diaryl compounds US Patent US8889668 Publication Date 11/18/2014
More Info.:Get all data from this article,  Assay Method
 
Sphingosine 1-phosphate receptor 1 (S1P1)
Name:Sphingosine 1-phosphate receptor 1 (S1P1)
Synonyms:Sphingosine 1-phosphate receptor | Sphingosine 1-phosphate receptor 1 (S1PR1) | Sphingosine 1-phosphate receptor Edg-1
Type:Enzyme
Mol. Mass.:42836.02
Organism:Homo sapiens (Human)
Description:P21453
Residue:382
Sequence:
MGPTSVPLVKAHRSSVSDYVNYDIIVRHYNYTGKLNISADKENSIKLTSVVFILICCFII
LENIFVLLTIWKTKKFHRPMYYFIGNLALSDLLAGVAYTANLLLSGATTYKLTPAQWFLR
EGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISACWVISLILGGLPIM
GWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIYSLVRTRSRRLTFRKN
ISKASRSSEKSLALLKTVIIVLSVFIACWAPLFILLLLDVGCKVKTCDILFRAEYFLVLA
VLNSGTNPIIYTLTNKEMRRAFIRIMSCCKCPSGDSAGKFKRPIIAGMEFSRSKSDNSSH
PQKDEGDNPETIMSSGNVNSSS
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM139213
NameBDBM139213
Synonyms:US8889668, I63
TypeSmall organic molecule
Emp. Form.C22H21F4N3O2
Mol. Mass.435.4147
SMILESCOc1ccc(F)cc1-c1noc(n1)-c1ccc(N2CCCCC2C)c(c1)C(F)(F)F
Structure
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