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TargetCyclophilin D (CypD)
LigandBDBM140005
Substrate/Competitorn/a
Meas. Tech.Enzymatic Assay
pH7.8±n/a
Temperature293.15±n/a K
IC50 640±n/a nM
Commentsextracted
Citation Guichou, JColliandre, LAhmed-Belkacem, HPawlotsky, J Inhibitors of cyclophilins and uses thereof US Patent US8901295 Publication Date 12/2/2014
More Info.:Get all data from this article,  Assay Method
 
Cyclophilin D (CypD)
Name:Peptidyl-prolyl cis-trans isomerase D
Synonyms:40 kDa peptidyl-prolyl cis-trans isomerase | CYP-40 | Cyclophilin-40 | Cyclophilin-related protein | PPIase D | Peptidyl-prolyl cis-trans isomerase D | Rotamase D
Type:Protein
Mol. Mass.:40766.62
Organism:Homo sapiens (Human)
Description:Q08752
Residue:370
Sequence:
MSHPSPQAKPSNPSNPRVFFDVDIGGERVGRIVLELFADIVPKTAENFRALCTGEKGIGH
TTGKPLHFKGCPFHRIIKKFMIQGGDFSNQNGTGGESIYGEKFEDENFHYKHDREGLLSM
ANAGRNTNGSQFFITTVPTPHLDGKHVVFGQVIKGIGVARILENVEVKGEKPAKLCVIAE
CGELKEGDDGGIFPKDGSGDSHPDFPEDADIDLKDVDKILLITEDLKNIGNTFFKSQNWE
MAIKKYAEVLRYVDSSKAVIETADRAKLQPIALSCVLNIGACKLKMSNWQGAIDSCLEAL
ELDPSNTKALYRRAQGWQGLKEYDQALADLKKAQGIAPEDKAIQAELLKVKQKIKAQKDK
EKAVYAKMFA
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BDBM140005
NameBDBM140005
Synonyms:US8901295, F684
TypeSmall organic molecule
Emp. Form.C21H26N4O2S
Mol. Mass.398.522
SMILESCSc1ccccc1C1CCCN1C(=O)CNC(=O)NCc1ccc(N)cc1
Structure
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