Ki Summary BindingDB logo
myBDB logout
Reaction Details
Report a problem with these data
TargetBradykinin B1 receptor
LigandBDBM140549
Substrate/Competitorn/a
Meas. Tech.Binding Assay
pH7.4±n/a
Ki 1.7±n/a nM
Commentsextracted
Citation Aebi, JBinggeli, AHertel, CKonkar, AAKuehne, HKuhn, BMaerki, HPWang, H Biaryl amide derivatives US Patent US8912221 Publication Date 12/16/2014
More Info.:Get all data from this article,  Assay Method
 
Bradykinin B1 receptor
Name:Bradykinin B1 receptor
Synonyms:B1 BRADYKININ | B1 bradykinin receptor | B1R | BK-1 receptor
Type:Enzyme
Mol. Mass.:40508.87
Organism:Homo sapiens (Human)
Description:P46663
Residue:353
Sequence:
MASSWPPLELQSSNQSQLFPQNATACDNAPEAWDLLHRVLPTFIISICFFGLLGNLFVLL
VFLLPRRQLNVAEIYLANLAASDLVFVLGLPFWAENIWNQFNWPFGALLCRVINGVIKAN
LFISIFLVVAISQDRYRVLVHPMASRRQQRRRQARVTCVLIWVVGGLLSIPTFLLRSIQA
VPDLNITACILLLPHEAWHFARIVELNILGFLLPLAAIVFFNYHILASLRTREEVSRTRC
GGRKDSKTTALILTLVVAFLVCWAPYHFFAFLEFLFQVQAVRGCFWEDFIDLGLQLANFF
AFTNSSLNPVIYVFVGRLFRTKVWELYKQCTPKSLAPISSSHRKEIFQLFWRN
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM140549
NameBDBM140549
Synonyms:US8912221, 22
TypeSmall organic molecule
Emp. Form.C22H18ClF5N6O3
Mol. Mass.544.862
SMILESC[C@@H](NC(=O)C1(COC1)NC(=O)C(F)(F)F)c1ccc(cc1F)-c1cc(Cl)cc(F)c1-c1nnn(C)n1 |r|
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a