Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM286136
Substrate
n/a
Meas. Tech.
AlphaScreen SureFire Assay
Temperature
298.15±n/a K
EC50
5070±n/a nM
Comments
extracted
Citation
 Shi, Y; Cheng, PT; Wang, Y; Wu, SC; Zhang, H Bicyclo [2.2.1] acid GPR120 modulators US Patent  US9518000 Publication Date 12/13/2016 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM286136
Synonyms:
4-(4-(2-methoxy- 5-(trifluorometh- oxy)benzyloxy) bicyclo[2.2.1] heptan-1-yl) butanoic acid | US9518000, Example 29 | US9518000, Example 30
Type:
Small organic molecule
Emp. Form.:
C20H23ClO3S
Mol. Mass.:
378.913
SMILES:
OC(=O)CCCC12CCC(CC1)(C2)OCc1csc2ccc(Cl)cc12
Structure:
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