Reaction Details Report a problem with these data
Target
Free fatty acid receptor 4
Ligand
BDBM286183
Substrate
n/a
Meas. Tech.
AlphaScreen SureFire Assay
Temperature
298.15±n/a K
EC50
3040±n/a nM
Comments
extracted
Citation
 Shi, Y; Cheng, PT; Wang, Y; Wu, SC; Zhang, H Bicyclo [2.2.1] acid GPR120 modulators US Patent  US9518000 Publication Date 12/13/2016 
Target
Name:
Free fatty acid receptor 4
Synonyms:
FFAR4 | FFAR4_HUMAN | G-protein coupled receptor 120 | G-protein coupled receptor 129 | G-protein coupled receptor GT01 | G-protein coupled receptor PGR4 | GPR120 | GPR129 | O3FAR1 | Omega-3 fatty acid receptor 1 | PGR4
Type:
PROTEIN
Mol. Mass.:
42256.91
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1508994
Residue:
377
Sequence:
MSPECARAAGDAPLRSLEQANRTRFPFFSDVKGDHRLVLAAVETTVLVLIFAVSLLGNVCALVLVARRRRRGATACLVLNLFCADLLFISAIPLVLAVRWTEAWLLGPVACHLLFYVMTLSGSVTILTLAAVSLERMVCIVHLQRGVRGPGRRARAVLLALIWGYSAVAALPLCVFFRVVPQRLPGADQEISICTLIWPTIPGEISWDVSFVTLNFLVPGLVIVISYSKILQTSEHLLDARAVVTHSEITKASRKRLTVSLAYSESHQIRVSQQDFRLFRTLFLLMVSFFIMWSPIIITILLILIQNFKQDLVIWPSLFFWVVAFTFANSALNPILYNMTLCRNEWKKIFCCFWFPEKGAILTDTSVKRNDLSIISG
  
Inhibitor
Name:
BDBM286183
Synonyms:
2-((4-(1-(3-fluoro-5-(4- fluorophenoxy)phenyl) ethoxy)bicyclo[2.2.1]heptan- 1-yl)methoxy)acetic acid | US9518000, Example 76
Type:
Small organic molecule
Emp. Form.:
C24H26F2O5
Mol. Mass.:
432.457
SMILES:
CC(OC12CCC(COCC(O)=O)(CC1)C2)c1cc(F)cc(Oc2ccc(F)cc2)c1
Structure:
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