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Target
Mandelate racemase
Ligand
BDBM152705
Substrate
n/a
Meas. Tech.
Circular Dichroism (CD) Based Assays
pH
7.5±n/a
Ki
1.800e+6± 3.00e+5 nM
Comments
extracted
Citation
 Nagar, M; Wyatt, BN; St Maurice, M; Bearne, SL Inactivation of Mandelate Racemase by 3-Hydroxypyruvate Reveals a Potential Mechanistic Link between Enzyme Superfamilies. Biochemistry 54:2747-57 (2015) [PubMed]  Article 
Target
Name:
Mandelate racemase
Synonyms:
MANR_PSEPU | Mandelate racemase | Mandelate racemase (MR) | mdlA
Type:
Protein
Mol. Mass.:
38561.77
Organism:
Pseudomonas putida (g-Proteobacteria)
Description:
n/a
Residue:
359
Sequence:
MSEVLITGLRTRAVNVPLAYPVHTAVGTVGTAPLVLIDLATSAGVVGHSYLFAYTPVALKSLKQLLDDMAAMIVNEPLAPVSLEAMLAKRFCLAGYTGLIRMAAAGIDMAAWDALGKVHETPLVKLLGANARPVQAYDSHSLDGVKLATERAVTAAELGFRAVKTKIGYPALDQDLAVVRSIRQAVGDDFGIMVDYNQSLDVPAAIKRSQALQQEGVTWIEEPTLQHDYEGHQRIQSKLNVPVQMGENWLGPEEMFKALSIGACRLAMPDAMKIGGVTGWIRASALAQQFGIPMSSHLFQEISAHLLAATPTAHWLERLDLAGSVIEPTLTFEGGNAVIPDLPGVGIIWREKEIGKYLV
  
Inhibitor
Name:
BDBM152705
Synonyms:
Mesoxalate
Type:
Small organic molecule
Emp. Form.:
C3O5
Mol. Mass.:
116.0302
SMILES:
[O-]C(=O)C(=O)C([O-])=O
Structure:
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