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Target
PHD finger protein 23
Ligand
BDBM154556
Substrate
n/a
Meas. Tech.
AlphaScreen Assay
pH
8±0
Temperature
1663.9±0 K
IC50
>1.00e+5±n/a nM
Citation
 Perfetti, MT; Baughman, BM; Dickson, BM; Mu, Y; Cui, G; Mader, P; Dong, A; Norris, JL; Rothbart, SB; Strahl, BD; Brown, PJ; Janzen, WP; Arrowsmith, CH; Mer, G; McBride, KM; James, LI; Frye, SV Identification of a fragment-like small molecule ligand for the methyl-lysine binding protein, 53BP1. ACS Chem Biol 10:1072-81 (2015) [PubMed]  Article 
Target
Name:
PHD finger protein 23
Synonyms:
PDH-containing protein JUNE-1 | PHD finger protein 23 | PHD finger protein 23 (PHF23) | PHF23 | PHF23_HUMAN
Type:
Protein
Mol. Mass.:
43813.67
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
403
Sequence:
MLEAMAEPSPEDPPPTLKPETQPPEKRRRTIEDFNKFCSFVLAYAGYIPPSKEESDWPASGSSSPLRGESAADSDGWDSAPSDLRTIQTFVKKAKSSKRRAAQAGPTQPGPPRSTFSRLQAPDSATLLEKMKLKDSLFDLDGPKVASPLSPTSLTHTSRPPAALTPVPLSQGDLSHPPRKKDRKNRKLGPGAGAGFGVLRRPRPTPGDGEKRSRIKKSKKRKLKKAERGDRLPPPGPPQAPPSDTDSEEEEEEEEEEEEEEMATVVGGEAPVPVLPTPPEAPRPPATVHPEGVPPADSESKEVGSTETSQDGDASSSEGEMRVMDEDIMVESGDDSWDLITCYCRKPFAGRPMIECSLCGTWIHLSCAKIKKTNVPDFFYCQKCKELRPEARRLGGPPKSGEP
  
Inhibitor
Name:
BDBM154556
Synonyms:
3-Bromo-N-(5-(tert-butylamino)pentyl)benzamide (12)
Type:
Small organic molecule
Emp. Form.:
C16H25BrN2O
Mol. Mass.:
341.286
SMILES:
CC(C)(C)NCCCCCNC(=O)c1cccc(Br)c1
Structure:
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