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Target5'-AMP-activated protein kinase subunit beta-1
LigandBDBM160333
Substrate/Competitorn/a
Meas. Tech.Kinase Assay
IC50 1122±n/a nM
Citation Hong, CCHopkins, CRHatzopoulos, AKLindsley, CWHao, J Compounds and methods useful for directing stem cell differentiation US Patent US9040694 Publication Date 5/26/2015
More Info.:Get all data from this article,  Assay Method
 
5'-AMP-activated protein kinase subunit beta-1
Name:5'-AMP-activated protein kinase subunit beta-1
Synonyms:5'-AMP-activated protein kinase subunit beta-1 (AMPK) | 5''''''''-AMP-activated protein kinase subunit beta-1 | 5''''-AMP-activated protein kinase catalytic subunit alpha-2/beta-1/gamma-2 | 5''''-AMP-activated protein kinase subunit beta-1 | 5''-AMP-activated protein kinase subunit beta-1 | AMP-activated protein kinase, beta-1 subunit | AMPK | AMPK subunit beta-1 | AMPKb | PRKAB1
Type:n/a
Mol. Mass.:30380.94
Organism:Homo sapiens (Human)
Description:Q9Y478
Residue:270
Sequence:
MGNTSSERAALERHGGHKTPRRDSSGGTKDGDRPKILMDSPEDADLFHSEEIKAPEKEEF
LAWQHDLEVNDKAPAQARPTVFRWTGGGKEVYLSGSFNNWSKLPLTRSHNNFVAILDLPE
GEHQYKFFVDGQWTHDPSEPIVTSQLGTVNNIIQVKKTDFEVFDALMVDSQKCSDVSELS
SSPPGPYHQEPYVCKPEERFRAPPILPPHLLQVILNKDTGISCDPALLPEPNHVMLNHLY
ALSIKDGVMVLSATHRYKKKYVTTLLYKPI
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM160333
NameBDBM160333
Synonyms:US9040694, 5
TypeSmall organic molecule
Emp. Form.C22H21N5
Mol. Mass.355.4356
SMILESC1CN(CCN1)c1ccc(cc1)-c1cnc2c(cnn2c1)-c1ccccc1
Structure
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n/a