Target
Alpha-synuclein
Ligand
BDBM170568
Substrate
n/a
Meas. Tech.
Competitive Binding Assay
pH
7.4±n/a
Ki
970±n/a nM
Comments
extracted
Citation
 Luke, EAYadon, MCCummings, JHudson, FMLake, THu, QCam, JSnow, AD Compounds for the treatment of neurodegenerative diseases US Patent  US9085549 Publication Date 7/21/2015 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM170568
Synonyms:
US9085549, 88
Type:
Small organic molecule
Emp. Form.:
C13H12N2O8
Mol. Mass.:
324.2441
SMILES:
Oc1cc(Cc2cc(O)c(O)cc2N([O-])=O)c(cc1O)N([O-])=O
Structure:
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