Reaction Details
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Beta-lactamase SHV-1
Ligand
BDBM178194
Substrate
n/a
Meas. Tech.
Cell Free Inhibition Assay
pH
7±n/a
Temperature
310.15±n/a K
IC50
4427.2±n/a nM
Comments
extracted
Citation
More Info.:
Target
Name:
Beta-lactamase SHV-1
Synonyms:
BLA1_ECOLX | Beta-lactamase (SHV-1) | bla | shv1
Type:
Enzyme
Mol. Mass.:
31226.68
Organism:
Escherichia coli
Description:
P0AD63
Residue:
286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
Inhibitor
Name:
BDBM178194
Synonyms:
US9120808, Example 14 | US9120808, Example 15
Type:
Small organic molecule
Emp. Form.:
C18H17NO5
Mol. Mass.:
327.3313
SMILES:
COC(=O)C1(CC=Cc2ccccc2)N2[C@@H](CC2=O)OC1=CC=O |w:6.5,21.24|
Structure:
