Reaction Details
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Beta-lactamase SHV-1
Ligand
BDBM178205
Substrate
n/a
Meas. Tech.
Cell Free Inhibition Assay
pH
7±n/a
Temperature
310.15±n/a K
IC50
6810.3±n/a nM
Comments
extracted
Citation
More Info.:
Target
Name:
Beta-lactamase SHV-1
Synonyms:
BLA1_ECOLX | Beta-lactamase (SHV-1) | bla | shv1
Type:
Enzyme
Mol. Mass.:
31226.68
Organism:
Escherichia coli
Description:
P0AD63
Residue:
286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADERFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCAAAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPASMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARGIVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
Inhibitor
Name:
BDBM178205
Synonyms:
US9120808, Example 38 | US9120808, Example 38a
Type:
Small organic molecule
Emp. Form.:
C18H19NO5
Mol. Mass.:
329.3472
SMILES:
OCC(CC=C)=C1O[C@@H]2CC(=O)N2C1C(=O)OCc1ccccc1 |w:6.14|
Structure:
