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TargetBeta-lactamase (SHV-1)
LigandBDBM178207
Substrate/Competitorn/a
Meas. Tech.Cell Free Inhibition Assay
pH7±n/a
Temperature310.15±n/a K
IC50 5609.9±n/a nM
Commentsextracted
Citation Bulusu, AR Substituted clavulanic acid US Patent US9120808 Publication Date 9/1/2015
More Info.:Get all data from this article,  Assay Method
 
Beta-lactamase (SHV-1)
Name:Beta-lactamase (SHV-1)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:31226.68
Organism:Escherichia coli
Description:P0AD63
Residue:286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE
RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA
AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA
SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG
IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM178207
NameBDBM178207
Synonyms:US9120808, Example 39
TypeSmall organic molecule
Emp. Form.C24H23NO5
Mol. Mass.405.4431
SMILESOCC(CC=Cc1ccccc1)=C1O[C@@H]2CC(=O)N2C1C(=O)OCc1ccccc1 |w:12.21,4.3|
Structure
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