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TargetBeta-lactamase (SHV-1)
LigandBDBM178214
Substrate/Competitorn/a
Meas. Tech.Cell Free Inhibition Assay
pH7±n/a
Temperature310.15±n/a K
IC50 22.6±n/a nM
Commentsextracted
Citation Bulusu, AR Substituted clavulanic acid US Patent US9120808 Publication Date 9/1/2015
More Info.:Get all data from this article,  Assay Method
 
Beta-lactamase (SHV-1)
Name:Beta-lactamase (SHV-1)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:31226.68
Organism:Escherichia coli
Description:P0AD63
Residue:286
Sequence:
MRYIRLCIISLLATLPLAVHASPQPLEQIKLSESQLSGRVGMIEMDLASGRTLTAWRADE
RFPMMSTFKVVLCGAVLARVDAGDEQLERKIHYRQQDLVDYSPVSEKHLADGMTVGELCA
AAITMSDNSAANLLLATVGGPAGLTAFLRQIGDNVTRLDRWETELNEALPGDARDTTTPA
SMAATLRKLLTSQRLSARSQRQLLQWMVDDRVAGPLIRSVLPAGWFIADKTGAGERGARG
IVALLGPNNKAERIVVIYLRDTPASMAERNQQIAGIGAALIEHWQR
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM178214
NameBDBM178214
Synonyms:US9120808, Example 57
TypeSmall organic molecule
Emp. Form.C19H21NO6
Mol. Mass.359.3731
SMILESCOC(=O)C1N2[C@@H](CC2=O)OC1=C(CCCc1ccccc1)C(=O)OC |w:11.12|
Structure
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