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TargetAmine oxidase (AGAO)
LigandBDBM185656
Substrate/Competitorn/a
Meas. Tech.Inhibition Assay
pH7.2±n/a
Temperature303.15±n/a K
IC50 250000±n/a nM
Commentsextracted
Citation Sayre, LM Amine oxidase inhibitors US Patent US9161922 Publication Date 10/20/2015
More Info.:Get all data from this article,  Assay Method
 
Amine oxidase (AGAO)
Name:Amine oxidase (AGAO)
Synonyms:n/a
Type:Enzyme
Mol. Mass.:75087.19
Organism:Arthrobacter globiformis
Description:Q59118
Residue:684
Sequence:
MTLQTTPSTPLVQDPPVPATLVHAAAQHPLEQLSAEEIHEARRILAEAGLVGESTRFAYL
GLIEPPKTTRQGDVTGAARLVRAMLWDAAQSRSLDVRLSLATGLVVDRRELNPEADGQLP
VLLEEFGIIEDILSEDPQWNAALTARGLTPAQVRVAPLSAGVFEYGNEEGKRLLRGLGFR
QDHPADHPWAHPIDGLVAFVDVENRRVNHLIDDGPVPVPEVNGNYTDPAIRGELRTDLLP
IEIMQPEGPSFTLEGNHLSWAGWDLRVGFDAREGLVLHQLHHSHKGRRRPVIHRASISEM
VVPYGDPSPYRSWQNYFDSGEYLVGRDANSLRLGCDCLGDITYMSPVVADDFGNPRTIEN
GICIHEEDAGILWKHTDEWAGSDEVRRNRRLVVSFFTTVGNYDYGFYWYLYLDGTIEFEA
KATGIVFTAALPDKDYAYASEIAPGLGAPYHQHLFSARLDMMIDGDANRVEELDLVRLPK
GPGNPHGNAFTQKRTLLARESEAVRDADGAKGRVWHISNPDSLNHLGHPVGYTLYPEGNP
TLAMADDSSIASRAAFARHHLWVTRHAEEELYAAGDFVNQHPGGAVLPAYVAQDRDIDGQ
DLVVWHSFGLTHFPRPEDWPIMPVDTTGFTLKPHGFFDENPTLNVPSSAAGHCGTGSERE
HAAPGGTAVGHSGPDTGGQGHCGH
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  Blast E-value cutoff:
BDBM185656
NameBDBM185656
Synonyms:US9161922, Table 3, Compound 1
TypeSmall organic molecule
Emp. Form.C14H19N3O
Mol. Mass.245.3202
SMILESNCC#CCC(N)C(=O)NCCc1ccccc1
Structure
Search PDB for entries with ligand similarity:Similarity to this molecule at least:
n/a