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Target
Histamine oxidase
Ligand
BDBM185658
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.2±n/a
Temperature
303.15±n/a K
IC50
7000±n/a nM
Comments
extracted
Citation
 Sayre, LM Amine oxidase inhibitors US Patent  US9161922 Publication Date 10/20/2015 
Target
Name:
Histamine oxidase
Synonyms:
AMOH_ARTGO | Amine oxidase (AGAO)
Type:
Enzyme
Mol. Mass.:
75087.19
Organism:
Arthrobacter globiformis
Description:
Q59118
Residue:
684
Sequence:
MTLQTTPSTPLVQDPPVPATLVHAAAQHPLEQLSAEEIHEARRILAEAGLVGESTRFAYLGLIEPPKTTRQGDVTGAARLVRAMLWDAAQSRSLDVRLSLATGLVVDRRELNPEADGQLPVLLEEFGIIEDILSEDPQWNAALTARGLTPAQVRVAPLSAGVFEYGNEEGKRLLRGLGFRQDHPADHPWAHPIDGLVAFVDVENRRVNHLIDDGPVPVPEVNGNYTDPAIRGELRTDLLPIEIMQPEGPSFTLEGNHLSWAGWDLRVGFDAREGLVLHQLHHSHKGRRRPVIHRASISEMVVPYGDPSPYRSWQNYFDSGEYLVGRDANSLRLGCDCLGDITYMSPVVADDFGNPRTIENGICIHEEDAGILWKHTDEWAGSDEVRRNRRLVVSFFTTVGNYDYGFYWYLYLDGTIEFEAKATGIVFTAALPDKDYAYASEIAPGLGAPYHQHLFSARLDMMIDGDANRVEELDLVRLPKGPGNPHGNAFTQKRTLLARESEAVRDADGAKGRVWHISNPDSLNHLGHPVGYTLYPEGNPTLAMADDSSIASRAAFARHHLWVTRHAEEELYAAGDFVNQHPGGAVLPAYVAQDRDIDGQDLVVWHSFGLTHFPRPEDWPIMPVDTTGFTLKPHGFFDENPTLNVPSSAAGHCGTGSEREHAAPGGTAVGHSGPDTGGQGHCGH
  
Inhibitor
Name:
BDBM185658
Synonyms:
US9161922, Table 3, Compound 3
Type:
Small organic molecule
Emp. Form.:
C9H17N3O
Mol. Mass.:
183.2508
SMILES:
CCCNC(=O)C(N)CC#CCN
Structure:
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