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Target
Protein Wnt-3a
Ligand
BDBM263601
Substrate
n/a
Meas. Tech.
WNT pathway reporter gene assay
IC50
8.00±n/a nM
Citation
 An, S Compound as WNT signaling inhibitor, composition, and use thereof US Patent  US10087181 Publication Date 10/2/2018 
Target
Name:
Protein Wnt-3a
Synonyms:
WNT3A | WNT3A_HUMAN
Type:
PROTEIN
Mol. Mass.:
39379.02
Organism:
Homo sapiens (Human)
Description:
ChEMBL_1469237
Residue:
352
Sequence:
MAPLGYFLLLCSLKQALGSYPIWWSLAVGPQYSSLGSQPILCASIPGLVPKQLRFCRNYVEIMPSVAEGIKIGIQECQHQFRGRRWNCTTVHDSLAIFGPVLDKATRESAFVHAIASAGVAFAVTRSCAEGTAAICGCSSRHQGSPGKGWKWGGCSEDIEFGGMVSREFADARENRPDARSAMNRHNNEAGRQAIASHMHLKCKCHGLSGSCEVKTCWWSQPDFRAIGDFLKDKYDSASEMVVEKHRESRGWVETLRPRYTYFKVPTERDLVYYEASPNFCEPNPETGSFGTRDRTCNVSSHGIDGCDLLCCGRGHNARAERRREKCRCVFHWCCYVSCQECTRVYDVHTCK
  
Inhibitor
Name:
BDBM263601
Synonyms:
US10087181, Compound 107 | US10285988, Compound 108 | US9713612, 108
Type:
Small organic molecule
Emp. Form.:
C28H22N6
Mol. Mass.:
442.5145
SMILES:
Cc1cc(ccn1)-c1cc2ccnc(NCc3ccc(-c4ccnc(C)c4)c(c3)C#N)c2cn1
Structure:
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