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TargetAlpha-1D adrenergic receptor
LigandBDBM186964
Substrate/Competitorn/a
Meas. Tech.Radioligand Binding Assay
pH7.4±n/a
Ki>10000±n/a nM
Commentsextracted
Citation Besnard, JHopkins, ALGilbert, IRuda, GFAbecassis, K Morpholino compounds, uses and methods US Patent US9079895 Publication Date 7/14/2015
More Info.:Get all data from this article,  Assay Method
 
Alpha-1D adrenergic receptor
Name:Alpha-1 adrenergic receptor
Synonyms:adrenergic Alpha2
Type:Enzyme
Mol. Mass.:59890.14
Organism:Mus musculus (Mouse)
Description:P97714
Residue:562
Sequence:
MTFRDILSVTFEGPRASSSTGGSGAGGGAGTVGPEGPAVGGVPGATGGSAVVGTGSGEDN
QSSTAEAGAAASGEVNGSAAVGGLVVSAQGVGVGVFLAAFILTAVAGNLLVILSVACNRH
LQTVTNYFIVNLAVADLLLSAAVLPFSATMEVLGFWPFGRTFCDVWAAVDVLCCTASILS
LCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWAVALVVSVGPLLGWKEPVPPDERFC
GITEEVGYAIFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGIKREPGKASEVVLRI
HCRGAATSAKGNPGTQSSKGHTLRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFF
VLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRRRR
RLWPSLRPPLASLDRRPALRLCPQPAHRTPRGSPSPHCTPRPGLRRHAGGAGFGLRPSKA
SLRLREWRLLGPLQRPTTQLRAKVSSLSHKFRSGGARRAETACALRSEVEAVSLNVPQDG
AEAVICQAYEPGDLSNLRETDI
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  Blast E-value cutoff:
BDBM186964
NameBDBM186964
Synonyms:US9079895, 66
TypeSmall organic molecule
Emp. Form.C23H28N2O3
Mol. Mass.380.48
SMILESCC1Cc2ccccc2N1C(=O)CN1CCO[C@@H](COc2ccccc2C)C1 |r|
Structure
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n/a