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Target
Vasopressin V1a receptor
Ligand
BDBM288793
Substrate
n/a
Meas. Tech.
competition binding assay
Temperature
298.15±n/a K
Ki
10.0±n/a nM
Comments
extracted
Citation
 Dolente, C; Fasching, B; Runtz-Schmitt, V; Schnider, P Spiro-thiazolones US Patent  US10092551 Publication Date 10/9/2018 
Target
Name:
Vasopressin V1a receptor
Synonyms:
AVPR V1a | AVPR1 | AVPR1A | Antidiuretic hormone receptor 1a | V1AR_HUMAN | V1aR | VASOPRESSIN V1A | Vascular/hepatic-type arginine vasopressin receptor | Vasopressin V1 receptor | Vasopressin V1a receptor | Vasopressin receptor
Type:
Receptor
Mol. Mass.:
46820.18
Organism:
Homo sapiens (Human)
Description:
P37288
Residue:
418
Sequence:
MRLSAGPDAGPSGNSSPWWPLATGAGNTSREAEALGEGNGPPRDVRNEELAKLEIAVLAVTFAVAVLGNSSVLLALHRTPRKTSRMHLFIRHLSLADLAVAFFQVLPQMCWDITYRFRGPDWLCRVVKHLQVFGMFASAYMLVVMTADRYIAVCHPLKTLQQPARRSRLMIAAAWVLSFVLSTPQYFVFSMIEVNNVTKARDCWATFIQPWGSRAYVTWMTGGIFVAPVVILGTCYGFICYNIWCNVRGKTASRQSKGAEQAGVAFQKGFLLAPCVSSVKSISRAKIRTVKMTFVIVTAYIVCWAPFFIIQMWSVWDPMSVWTESENPTITITALLGSLNSCCNPWIYMFFSGHLLQDCVQSFPCCQNMKEKFNKEDTDSMSRRQTFYSNNRSPTNSTGMWKDSPKSSKSIKFIPVST
  
Inhibitor
Name:
BDBM288793
Synonyms:
US10092551, Example 101
Type:
Small organic molecule
Emp. Form.:
C28H22F2N2O2S
Mol. Mass.:
488.548
SMILES:
Fc1ccc(cc1)-[#6](=[#6]-1/[#16]-[#6](=[#7]-[#6]-1=O)-[#7]-1-[#6]-[#6]C2([#6]-[#6]-1)[#8]-[#6]-c1ccccc21)\c1ccc(F)cc1 |c:11|
Structure:
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