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Target
Transcription factor Jun
Ligand
BDBM191747
Substrate
n/a
Meas. Tech.
Cellular Firefly Luciferase Assay (AP-1)
IC50
8300±n/a nM
Citation
 Vander Jagt, DL; Deck, LM; Abcouwer, SF; Orlando, RA; Royer, RE; Weber, WM; Bobrovnikova-Marjon, EV; Hunsaker, LA Therapeutic curcumin derivatives US Patent  US9187397 Publication Date 11/17/2015 
Target
Name:
Transcription factor Jun
Synonyms:
AP1 | Activator protein 1 | JUN | JUN_HUMAN | Proto-oncogene c-JUN | Transcription factor AP-1 | Transcription factor AP1 | V-jun avian sarcoma virus 17 oncogene homolog | p39
Type:
n/a
Mol. Mass.:
35683.24
Organism:
Homo sapiens (Human)
Description:
P05412
Residue:
331
Sequence:
MTAKMETTFYDDALNASFLPSESGPYGYSNPKILKQSMTLNLADPVGSLKPHLRAKNSDLLTSPDVGLLKLASPELERLIIQSSNGHITTTPTPTQFLCPKNVTDEQEGFAEGFVRALAELHSQNTLPSVTSAAQPVNGAGMVAPAVASVAGGSGSGGFSASLHSEPPVYANLSNFNPGALSSGGGAPSYGAAGLAFPAQPQQQQQPPHHLPQQMPVQHPRLQALKEEPQTVPEMPGETPPLSPIDMESQERIKAERKRMRNRIAASKCRKRKLERIARLEEKVKTLKAQNSELASTANMLREQVAQLKQKVMNHVNSGCQLMLTQQLQTF
  
Inhibitor
Name:
BDBM191747
Synonyms:
US9187397, 20ag
Type:
Small organic molecule
Emp. Form.:
C23H22O7
Mol. Mass.:
410.4166
SMILES:
COc1cc(\C=C\C(=O)\C=C\c2ccc(OC(C)=O)c(OC)c2)ccc1OC(C)=O
Structure:
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