Reaction Details Report a problem with these data
Target
Cathepsin B
Ligand
BDBM192668
Substrate
n/a
Meas. Tech.
Proteolytic Activity Assay
pH
5±0
Temperature
310.15±0 K
Ki
664±0.0 nM
Citation
 Garg, S; Raghav, N 2,5-Diaryloxadiazoles and their precursors as novel inhibitors of cathepsins B, H and L. Bioorg Chem 67:64-74 (2016) [PubMed]  Article 
Target
Name:
Cathepsin B
Synonyms:
n/a
Type:
Protein
Mol. Mass.:
36777.57
Organism:
Capra hircus (Goat)
Description:
n/a
Residue:
335
Sequence:
MWQLLATLSCLLVLTSARSSLHFPPLSDEMVNYVNKQNTTWKAGHNFYNVDLSYVKKLCGAILGGPKLPQRDAFAADMVLPDSFDAREQWPNCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHSKGRVNVEVSAEDMLTCCGSECGDGCNGGFPSGAWNFWTKKGLVSGGLYDSHVGCRPYSIPPCEHHVNGSRPPCTGEGDTPKCSKICEPGYSPSYKDDKHFGCSSYSVSSNEKEIMAEIYKNGPVEGAFSVYSDFLLYKSGVYQHVSGEMMGGHAIRILGWGVENDTPYWLVGNSWNTDWGDKGFFKILRGQDHCGIESEIVAGMPCTHQY
  
Inhibitor
Name:
BDBM192668
Synonyms:
2-phenyl-5-(4-nitrophenyl)-1,3,4-oxadiazole (2k)
Type:
Small organic molecule
Emp. Form.:
C14H9N3O3
Mol. Mass.:
267.2396
SMILES:
[O-][N+](=O)c1ccc(cc1)-c1nnc(o1)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: