Reaction Details Report a problem with these data
Target
Serine protease 1
Ligand
BDBM193319
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
8±n/a
Temperature
298.15±n/a K
IC50
0.26±n/a nM
Comments
extracted
Citation
 Fujiyasu, J; Ohne, K; Yamaki, S; Imaizumi, T; Hondo, T; Matsuura, K; Satou, T; Sasamura, S Guanidinobenzoic acid compound US Patent  US9199927 Publication Date 12/1/2015 
Target
Name:
Serine protease 1
Synonyms:
Alpha-trypsin chain 1 | Alpha-trypsin chain 2 | Beta-trypsin | Cationic trypsinogen | PRSS1 | Serine protease 1 | TRP1 | TRY1 | TRY1_HUMAN | TRYP1 | Thrombin & trypsin | Trypsin | Trypsin I | Trypsin-1
Type:
Enzyme
Mol. Mass.:
26557.80
Organism:
Homo sapiens (Human)
Description:
P07477
Residue:
247
Sequence:
MNPLLILTFVAAALAAPFDDDDKIVGGYNCEENSVPYQVSLNSGYHFCGGSLINEQWVVSAGHCYKSRIQVRLGEHNIEVLEGNEQFINAAKIIRHPQYDRKTLNNDIMLIKLSSRAVINARVSTISLPTAPPATGTKCLISGWGNTASSGADYPDELQCLDAPVLSQAKCEASYPGKITSNMFCVGFLEGGKDSCQGDSGGPVVCNGQLQGVVSWGDGCAQKNKPGVYTKVYNYVKWIKNTIAANS
  
Inhibitor
Name:
BDBM193319
Synonyms:
US9199927, 30
Type:
Small organic molecule
Emp. Form.:
C25H22ClFN4O5
Mol. Mass.:
512.917
SMILES:
NC(=N)Nc1ccc(cc1)C(=O)Oc1ccc(CC(=O)N[C@@H](Cc2cccc(F)c2)C(O)=O)c(Cl)c1 |r|
Structure:
Search PDB for entries with ligand similarity: