Reaction Details Report a problem with these data
Target
Tyrosine-protein kinase transforming protein Src [144-247]
Ligand
BDBM195582
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assay
pH
7.35±n/a
Kd
9620±1670 nM
Comments
extracted
Citation
 Ju, T; Niu, W; Guo, J Evolution of Src Homology 2 (SH2) Domain to Recognize Sulfotyrosine. ACS Chem Biol 11:2551-7 (2016) [PubMed]  Article 
Target
Name:
Tyrosine-protein kinase transforming protein Src [144-247]
Synonyms:
SRC_RSVSA | Src homology 2 domain (SH2-wt) | V-SRC
Type:
Protein
Mol. Mass.:
11957.88
Organism:
Rous sarcoma virus (Virus)
Description:
PDB code 1SPS
Residue:
104
Sequence:
QAEEWYFGKITRRESERLLLNPENPRGTFLVRESETTKGAYCLSVSDFDNAKGLNVKHYKIRKLDSGGFYITSRTQFSSLQQLVAYYSKHADGLCHRLTNVCPT
  
Inhibitor
Name:
BDBM195582
Synonyms:
Sulfotyrosine (sTyr)
Type:
Small organic molecule
Emp. Form.:
C9H10NO6S
Mol. Mass.:
260.244
SMILES:
[NH3+][C@@H](Cc1ccc(OS([O-])(=O)=O)cc1)C([O-])=O |r|
Structure:
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