Reaction Details Report a problem with these data
Target
Androgen-dependent TFPI-regulating protein
Ligand
BDBM195603
Substrate
n/a
Meas. Tech.
Gel-based ABPP Assay
IC50
1.3e+3± 4e+2 nM
Citation
 Parsons, WH; Kolar, MJ; Kamat, SS; Cognetta, AB; Hulce, JJ; Saez, E; Kahn, BB; Saghatelian, A; Cravatt, BF AIG1 and ADTRP are atypical integral membrane hydrolases that degrade bioactive FAHFAs. Nat Chem Biol 12:367-72 (2016) [PubMed]  Article 
Target
Name:
Androgen-dependent TFPI-regulating protein
Synonyms:
ADTRP | ADTRP_HUMAN | Androgen-dependent TFPI-regulating protein (ADTRP) | C6orf105
Type:
Protein
Mol. Mass.:
26858.19
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
230
Sequence:
MTKTSTCIYHFLVLSWYTFLNYYISQEGKDEVKPKILANGARWKYMTLLNLLLQTIFYGVTCLDDVLKRTKGGKDIKFLTAFRDLLFTTLAFPVSTFVFLAFWILFLYNRDLIYPKVLDTVIPVWLNHAMHTFIFPITLAEVVLRPHSYPSKKTGLTLLAAASIAYISRILWLYFETGTWVYPVFAKLSLLGLAAFFSLSYVFIASIYLLGEKLNHWKWGDMRQPRKKRK
  
Inhibitor
Name:
BDBM195603
Synonyms:
KC01
Type:
Small organic molecule
Emp. Form.:
C22H39NO3
Mol. Mass.:
365.55
SMILES:
CCCCCCCCCCCCCC1OC(=O)\C1=C/CCCCC(N)=O
Structure:
Search PDB for entries with ligand similarity: