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Target
Prolactin-releasing peptide receptor
Ligand
BDBM195753
Substrate
n/a
Meas. Tech.
Inhibition Assay
pH
7.4±n/a
Temperature
298.15±n/a K
Ki
6±n/a nM
Comments
extracted
Citation
 Takahashi, A; Suzuki, M; Nakamura, Y; Sakurai, Y Heterocyclic compounds for the treatment of stress-related conditions US Patent  US9206173 Publication Date 12/8/2015 
Target
Name:
Prolactin-releasing peptide receptor
Synonyms:
G-protein coupled receptor 10 (GPR10) | GPR10 | GR3 | PRLHR | PRLHR_HUMAN | Prolactin Releasing Peptide Receptor | Prolactin-releasing peptide receptor
Type:
Protein
Mol. Mass.:
41138.32
Organism:
Homo sapiens (Human)
Description:
P49683
Residue:
370
Sequence:
MASSTTRGPRVSDLFSGLPPAVTTPANQSAEASAGNGSVAGADAPAVTPFQSLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCTACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRISLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLLVTYLLPLLVILLSYVRVSVKLRNRVVPGCVTQSQADWDRARRRRTFCLLVVIVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNPFIYAWLHDSFREELRKLLVAWPRKIAPHGQNMTVSVVI
  
Inhibitor
Name:
BDBM195753
Synonyms:
US9206173, 166
Type:
Small organic molecule
Emp. Form.:
C28H26F4N6O2
Mol. Mass.:
554.5387
SMILES:
C[C@@H](Nc1nc2CCN(Cc2c(=O)n1N1CCCC1)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F |r|
Structure:
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