Reaction Details Report a problem with these data
Target
Macrophage colony-stimulating factor 1 receptor [555-568]
Ligand
BDBM50443132
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Competition Immunoassay
pH
7.5±n/a
IC50
1.43±n/a nM
Comments
extracted
Citation
 Illig, CR; Ballentine, SK; Chen, J; Desjarlais, RL; Meegalla, SK; Wall, M; Wilson, K Inhibitors of c-fms kinase US Patent  US9221797 Publication Date 12/29/2015 
Target
Name:
Macrophage colony-stimulating factor 1 receptor [555-568]
Synonyms:
CSF1R | CSF1R_HUMAN | FMS | FMS (aa 555-568) peptide | FMS Substrate Peptide (aa 555-568) | Macrophage colony-stimulating factor 1 receptor (CSF1R) or (c-fms)
Type:
Peptide
Mol. Mass.:
1619.64
Organism:
Homo sapiens (Human)
Description:
P07333 aa 555-568
Residue:
14
Sequence:
SYEGNSYTFIDPTQ
  
Inhibitor
Name:
BDBM50443132
Synonyms:
CHEMBL3086175 | US9221797, 42
Type:
Small organic molecule
Emp. Form.:
C23H27N5O2
Mol. Mass.:
405.4928
SMILES:
O=C(Nc1ccc(CCN2CCOCC2)cc1C1=CCCCC1)c1ncc([nH]1)C#N |t:19|
Structure:
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