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TargetBET bromodomain 3(2) (BRD3(2))
LigandBDBM205429
Substrate/Competitorn/a
Meas. Tech.Bromodomains Assay for DiscoveRx Gene Symbol
Kd 19±0.0 nM
Citation Tanaka, MRoberts, JMSeo, HSSouza, APaulk, JScott, TGDeAngelo, SLDhe-Paganon, SBradner, JE Design and characterization of bivalent BET inhibitors. Nat Chem Biol12:1089-1096 (2016) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
BET bromodomain 3(2) (BRD3(2))
Name:BET bromodomain 3(2) (BRD3(2))
Synonyms:n/a
Type:n/a
Mol. Mass.:13068.97
Organism:Homo sapiens (Human)
Description:Q15059 (BRD3, 306-416)
Residue:111
Sequence:
GKLSEHLRYCDSILREMLSKKHAAYAWPFYKPVDAEALELHDYHDIIKHPMDLSTVKRKM
DGREYPDAQGFAADVRLMFSNCYKYNPPDHEVVAMARKLQDVFEMRFAKMP
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM205429
NameBDBM205429
Synonyms: (R)-JQ1 (3) | US10407441, Compound (R)-JQ1 | US9320741, (R)-JQ1
TypeSmall organic molecule
Emp. Form.C23H25ClN4O2S
Mol. Mass.456.988
SMILESCc1nnc2[C@@H](CC(=O)OC(C)(C)C)N=C(c3c(C)c(C)sc3-n12)c1ccc(Cl)cc1 |r,c:14|
Structure
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