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Target
Alpha-synuclein
Ligand
BDBM207866
Substrate
n/a
Meas. Tech.
In Vitro Inhibition Assay
EC50
94±n/a nM
Citation
 Griffioen, G; Van Dooren, T; Rojas De La Parra, V; Allasia, S; Marchand, A; Kilonda, A; Chaltin, P Compounds for the treatment of neurodegenerative diseases US Patent  US9266832 Publication Date 2/23/2016 
Target
Name:
Alpha-synuclein
Synonyms:
NACP | PARK1 | SNCA | SYUA_HUMAN
Type:
Protein
Mol. Mass.:
14451.42
Organism:
Homo sapiens (Human)
Description:
P37840
Residue:
140
Sequence:
MDVFMKGLSKAKEGVVAAAEKTKQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTAVAQKTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEEGYQDYEPEA
  
Inhibitor
Name:
BDBM207866
Synonyms:
US9266832, Cpd023
Type:
Small organic molecule
Emp. Form.:
C25H24ClN3O
Mol. Mass.:
417.931
SMILES:
Clc1ccc2[nH]cc(CCNC(=O)c3cccc(CNCc4ccccc4)c3)c2c1
Structure:
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