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Target
Taste receptor type 2 member 14
Ligand
BDBM211119
Substrate
n/a
Meas. Tech.
Fluorescence Polarization Assays
IC50
188.00±n/a nM
Citation
 Karanewsky, DS; Fotsing, JR; Tachdjian, C; Arellano, M Identification of human T2R receptors that respond to bitter compounds that elicit the bitter taste in compositions, and the use thereof in assays to identify compounds that inhibit (block) bitter taste in compositions and use thereof US Patent  US9247759 Publication Date 2/2/2016 
Target
Name:
Taste receptor type 2 member 14
Synonyms:
T2R14 | T2R14_HUMAN | TAS2R14 | TRB1 | Taste receptor family B member 1
Type:
n/a
Mol. Mass.:
36183.39
Organism:
Homo sapiens (Human)
Description:
Q9NYV8
Residue:
317
Sequence:
MGGVIKSIFTFVLIVEFIIGNLGNSFIALVNCIDWVKGRKISSVDRILTALAISRISLVWLIFGSWCVSVFFPALFATEKMFRMLTNIWTVINHFSVWLATGLGTFYFLKIANFSNSIFLYLKWRVKKVVLVLLLVTSVFLFLNIALINIHINASINGYRRNKTCSSDSSNFTRFSSLIVLTSTVFIFIPFTLSLAMFLLLIFSMWKHRKKMQHTVKISGDASTKAHRGVKSVITFFLLYAIFSLSFFISVWTSERLEENLIILSQVMGMAYPSCHSCVLILGNKKLRQASLSVLLWLRYMFKDGEPSGHKEFRESS
  
Inhibitor
Name:
BDBM211119
Synonyms:
US9247759, 5-43
Type:
Small organic molecule
Emp. Form.:
C22H21NO6S
Mol. Mass.:
427.47
SMILES:
COc1cccc(CN(Cc2ccc(cc2)C(O)=O)S(=O)(=O)c2ccc(O)cc2)c1
Structure:
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