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Target
C-terminal-binding protein 1 [R266Q]
Ligand
BDBM213227
Substrate
n/a
Meas. Tech.
Equilibrium Dialysis
Kd
1.6e+3±n/a nM
Citation
 Madison, DL; Wirz, JA; Siess, D; Lundblad, JR Nicotinamide adenine dinucleotide-induced multimerization of the co-repressor CtBP1 relies on a switching tryptophan. J Biol Chem 288:27836-48 (2013) [PubMed]  Article 
Target
Name:
C-terminal-binding protein 1 [R266Q]
Synonyms:
C-terminal binding protein (CtBP1 R266Q) | CTBP | CTBP1 | CTBP1_HUMAN
Type:
Protein
Mol. Mass.:
47508.73
Organism:
Homo sapiens (Human)
Description:
Human CtBP1 R266Q mutant
Residue:
440
Sequence:
MGSSHLLNKGLPLGVRPPIMNGPLHPRPLVALLDGRDCTVEMPILKDVATVAFCDAQSTQEIHEKVLNEAVGALMYHTITLTREDLEKFKALRIIVRIGSGFDNIDIKSAGDLGIAVCNVPAASVEETADSTLCHILNLYRRATWLHQALREGTRVQSVEQIREVASGAARIRGETLGIIGLGRVGQAVALRAKAFGFNVLFYDPYLSDGVERALGLQRVSTLQDLLFHSDCVTLHCGLNEHNHHLINDFTVKQMRQGAFLVNTAQGGLVDEKALAQALKEGRIRGAALDVHESEPFSFSQGPLKDAPNLICTPHAAWYSEQASIEMREEAAREIRRAITGRIPDSLKNCVNKDHLTAATHWASMDPAVVHPELNGAAYRYPPGVVGVAPTGIPAAVEGIVPSAMSLSHGLPPVAHPPHAPSPGQTVKPEADRDHASDQL
  
Inhibitor
Name:
BDBM213227
Synonyms:
Nicotinamide adenine dinucleotide (NAD)
Type:
Small organic molecule
Emp. Form.:
C21H27N7O14P2
Mol. Mass.:
663.4251
SMILES:
NC(=O)c1ccc[n+](c1)[C@@H]1O[C@H](COP([O-])(=O)OP(O)(=O)OC[C@H]2O[C@H]([C@H](O)[C@@H]2O)n2cnc3c(N)ncnc23)[C@@H](O)[C@H]1O
Structure:
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