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Target
Baculoviral IAP repeat-containing protein 2 [256-363]
Ligand
BDBM213392
Substrate
n/a
Meas. Tech.
XIAP BIR3 & cIAP1 BIR3 Binding Assays (DELFIA)
Temperature
298.15±n/a K
IC50
136±n/a nM
Comments
extracted
Citation
 Reiser, U; Madden, J 6-Alkynyl Pyridine US Patent  US9278978 Publication Date 3/8/2016 
Target
Name:
Baculoviral IAP repeat-containing protein 2 [256-363]
Synonyms:
API1 | BIRC2 | BIRC2_HUMAN | Cellular inhibitor of apoptosis 1 (c-IAP1/BIR3) | Cellular inhibitor of apoptosis 1 BIR3 domain (c-IAP1 BIR3) | IAP repeat-containing protein 2 (cIAP1) BIR-3 | MIHB | RNF48
Type:
Enzyme
Mol. Mass.:
12600.71
Organism:
Homo sapiens (Human)
Description:
Human cIAP BIR3 domain (256-363 aa)
Residue:
108
Sequence:
TLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGRNDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLLSTS
  
Inhibitor
Name:
BDBM213392
Synonyms:
US9278978, 27
Type:
Small organic molecule
Emp. Form.:
C27H24N4O2
Mol. Mass.:
436.5051
SMILES:
CN[C@H](C)C(=O)Nc1cc(c(OC)c(n1)C#Cc1ccccc1)-c1cccc2ncccc12 |r|
Structure:
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