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Target
Interleukin-2
Ligand
BDBM161749
Substrate
n/a
Meas. Tech.
IL-2 ELISA Assay
EC50
<10000±n/a nM
Citation
 Singh, R; Duncton, M; Zhang, J; Alvarez, S; Tso, K; Holland, S; Yen, R; Kolluri, R; Heckrodt, T; Chen, Y; Masuda, E; Li, H; Payan, DG; Kelley, R Protein kinase C inhibitors and uses thereof US Patent  US9682976 Publication Date 6/20/2017 
Target
Name:
Interleukin-2
Synonyms:
IL-2 | IL2 | IL2_HUMAN | INN=Aldesleukin | Interleukin-2 | Interleukin-2 (IL-2) | T-cell growth factor | TCGF
Type:
Enzyme
Mol. Mass.:
17630.05
Organism:
Homo sapiens (Human)
Description:
P60568
Residue:
153
Sequence:
MYRMQLLSCIALSLALVTNSAPTSSSTKKTQLQLEHLLLDLQMILNGINNYKNPKLTRMLTFKFYMPKKATELKHLQCLEEELKPLEEVLNLAQSKNFHLRPRDLISNINVIVLELKGSETTFMCEYADETATIVEFLNRWITFCQSIISTLT
  
Inhibitor
Name:
BDBM161749
Synonyms:
US9682976, 191
Type:
Small organic molecule
Emp. Form.:
C33H41F2N9O9
Mol. Mass.:
745.7303
SMILES:
CC(=O)O[C@@H]1COC(Oc2cc(F)c(Nc3ncc(F)c(N[C@@H]4C[C@@H]5CCCN5C(C)(C)C4)n3)cc2-n2nnn(C)c2=O)[C@@H](OC(C)=O)[C@@H]1OC(C)=O |r|
Structure:
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