Reaction Details Report a problem with these data
Target
RAC-alpha serine/threonine-protein kinase [1-123]
Ligand
BDBM50304369
Substrate
n/a
Meas. Tech.
Cellular Assay
IC50
10000±n/a nM
Citation
 Mahadevan, D; Meuillet, EJ; Mash, Jr., EA; Gokhale, VM; Powis, G; Zhang, S Small molecule inhibitors of the pleckstrin homology domain and methods for using same US Patent  US9320734 Publication Date 4/26/2016 
Target
Name:
RAC-alpha serine/threonine-protein kinase [1-123]
Synonyms:
AKT1 | AKT1_HUMAN | PKB | RAC | RAC-alpha serine/threonine-protein kinase (Akt)
Type:
Enzyme
Mol. Mass.:
14664.42
Organism:
Homo sapiens (Human)
Description:
PLECKSTRIN HOMOLOGY DOMAIN RESIDUES 1-123 (PH Domain)
Residue:
123
Sequence:
MSDVAIVKEGWLHKRGEYIKTWRPRYFLLKNDGTFIGYKERPQDVDQREAPLNNFSVAQCQLMKTERPRPNTFIIRCLQWTTVIERTFHVETPEEREEWTTAIQTVADGLKKQEEEEMDFRSG
  
Inhibitor
Name:
BDBM50304369
Synonyms:
4-dodecyl-N-(1,3,4-thiadiazol-2-yl)benzenesulfonamide | CHEMBL595583 | US9320734, 104
Type:
Small organic molecule
Emp. Form.:
C20H31N3O2S2
Mol. Mass.:
409.609
SMILES:
CCCCCCCCCCCCc1ccc(cc1)S(=O)(=O)Nc1nncs1
Structure:
Search PDB for entries with ligand similarity: