Reaction Details Report a problem with these data
Target
Lysophosphatidic acid receptor 3
Ligand
BDBM50398093
Substrate
n/a
Meas. Tech.
Calcium Flux Assay Using Fluorometric Imaging Plate Reader (FLIPR) Assay
Temperature
298.15±n/a K
IC50
132±n/a nM
Comments
extracted
Citation
 Gabriel, SD; Hamilton, MM; Lucas, MC; Qian, Y; Sidduri, A N-alkyltriazole compounds as LPAR antagonists US Patent  US9321738 Publication Date 4/26/2016 
Target
Name:
Lysophosphatidic acid receptor 3
Synonyms:
EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7
Type:
Enzyme
Mol. Mass.:
40149.72
Organism:
Homo sapiens (Human)
Description:
Q9UBY5
Residue:
353
Sequence:
MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKTVMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
  
Inhibitor
Name:
BDBM50398093
Synonyms:
CHEMBL2182046 | US9321738, 6
Type:
Small organic molecule
Emp. Form.:
C29H25F3N4O4
Mol. Mass.:
550.5284
SMILES:
C[C@@H](OC(=O)Nc1c(nnn1C)-c1ccc(cc1)-c1ccc(cc1)C1(CC1)C(O)=O)c1cccc(c1)C(F)(F)F |r|
Structure:
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