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Target
Serine/threonine-protein kinase Chk1 [2-280]
Ligand
BDBM50218734
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
17200±n/a nM
Citation
 D3R, DD Abbott CHK1 Kinase D3R 221:0 (2015) [PubMed] 
Target
Name:
Serine/threonine-protein kinase Chk1 [2-280]
Synonyms:
CHEK1 | CHK1 | CHK1_HUMAN | CHK1_Kinase
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
O14757[2-280]
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
  
Inhibitor
Name:
BDBM50218734
Synonyms:
8-chloro-5,10-dihydro-dibenzo[b,e][1,4]diazepin-11-one | 8-chloro-5H-dibenzo[b,e][1,4]diazepin-11(10H)-one | CHEMBL396034 | Chk1_8
Type:
Small organic molecule
Emp. Form.:
C13H9ClN2O
Mol. Mass.:
244.676
SMILES:
Clc1ccc2Nc3ccccc3C(=O)Nc2c1
Structure:
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