Reaction Details
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Serine/threonine-protein kinase Chk1 [2-280]
Ligand
BDBM91939
Substrate
n/a
Meas. Tech.
33P-Radiometric_Method1
Ki
76.8±n/a nM
More Info.:
Target
Name:
Serine/threonine-protein kinase Chk1 [2-280]
Synonyms:
CHEK1 | CHK1 | CHK1_HUMAN | CHK1_Kinase
Type:
n/a
Mol. Mass.:
32109.16
Organism:
Homo sapiens (Human)
Description:
O14757[2-280]
Residue:
279
Sequence:
AVPFVEDWDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENIKKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDIGMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLAGELPWDQPSDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRWYNKPLKKGAKRPRVTS
Inhibitor
Name:
BDBM91939
Synonyms:
Chk1_70
Type:
n/a
Emp. Form.:
C21H16N2O4
Mol. Mass.:
360.3627
SMILES:
COc1cc(ccc1C(O)=O)-c1ccc2c(Nc3ccccc3NC2=O)c1
Structure:
