Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Ligand
BDBM92312
Substrate
n/a
Meas. Tech.
Photometric_Method1
Ki
>100000±n/a nM
Citation
 D3R, DD Abbott Urokinase D3R 227:0 (2015) [PubMed] 
Target
Name:
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Synonyms:
PLAU | UROK_HUMAN | Urokinase
Type:
n/a
Mol. Mass.:
27687.84
Organism:
Homo sapiens (Human)
Description:
P00749[179-424,C299A,N323Q]
Residue:
246
Sequence:
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
  
Inhibitor
Name:
BDBM92312
Synonyms:
uPa_35
Type:
n/a
Emp. Form.:
C13H12N4O
Mol. Mass.:
240.2606
SMILES:
CN(CC#N)C(=O)c1ccc2ccc(N)nc2c1
Structure:
Search PDB for entries with ligand similarity: