Reaction Details Report a problem with these data
Target
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Ligand
BDBM50138662
Substrate
n/a
Meas. Tech.
Photometric_Method1
Ki
40±n/a nM
Citation
 D3R, DD Abbott Urokinase D3R 227:0 (2015) [PubMed] 
Target
Name:
Urokinase-type plasminogen activator [179-424,C299A,N323Q]
Synonyms:
PLAU | UROK_HUMAN | Urokinase
Type:
n/a
Mol. Mass.:
27687.84
Organism:
Homo sapiens (Human)
Description:
P00749[179-424,C299A,N323Q]
Residue:
246
Sequence:
IIGGEFTTIENQPWFAAIYRRHRGGSVTYVCGGSLISPCWVISATHCFIDYPKKEDYIVYLGRSRLNSNTQGEMKFEVENLILHKDYSADTLAHHNDIALLKIRSKEGRCAQPSRTIQTIALPSMYNDPQFGTSCEITGFGKEQSTDYLYPEQLKMTVVKLISHRECQQPHYYGSEVTTKMLCAADPQWKTDSCQGDSGGPLVCSLQGRMTLTGIVSWGRGCALKDKPGVYTRVSHFLPWIRSHTK
  
Inhibitor
Name:
BDBM50138662
Synonyms:
6-Carbamimidoyl-naphthalene-2-carboxylic acid (4-aminomethyl-phenyl)-amide | 6-[(Z)-AMINO(IMINO)METHYL]-N-[4-(AMINOMETHYL)PHENYL]-2-NAPHTHAMIDE | CHEMBL324168 | N-(4-(aminomethyl)phenyl)-6-carbamimidoyl-2-naphthamide | uPa_9
Type:
Small organic molecule
Emp. Form.:
C19H18N4O
Mol. Mass.:
318.3724
SMILES:
NCc1ccc(NC(=O)c2ccc3cc(ccc3c2)C(N)=N)cc1
Structure:
Search PDB for entries with ligand similarity: