Reaction Details Report a problem with these data
Target
Cannabinoid receptor 1
Ligand
BDBM50335938
Substrate
n/a
Meas. Tech.
Binding Assay
pH
7.4±n/a
Ki
>10000±n/a nM
Comments
extracted
Citation
 Attala, MN; Diaz, P Heterocyclic modulators of cannabinoid receptors US Patent  US9339486 Publication Date 5/17/2016 
Target
Name:
Cannabinoid receptor 1
Synonyms:
CANN6 | CANNABINOID CB1 | CB-R | CB1 | CNR | CNR1 | CNR1_HUMAN | Cannabinoid CB1 receptor | Cannabinoid receptor | Cannabinoid receptor 1 (CB1) | Cannabinoid receptor 1 (brain)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
52868.96
Organism:
Homo sapiens (Human)
Description:
P21554
Residue:
472
Sequence:
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQPLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
  
Inhibitor
Name:
BDBM50335938
Synonyms:
(3-benzyl-3-methyl-2,3-dihydrobenzofuran-6-yl)(piperidin-1-yl)methanone | CHEMBL495528 | US9339486, 3
Type:
Small organic molecule
Emp. Form.:
C22H25NO2
Mol. Mass.:
335.4394
SMILES:
CC1(Cc2ccccc2)COc2cc(ccc12)C(=O)N1CCCCC1
Structure:
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