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Target
Fatty acid-binding protein 5-ANS
Ligand
BDBM22319
Substrate
n/a
Meas. Tech.
Fluorescence Competition Assay
Kd
42.1±4.1 nM
Citation
 Yu, S; Levi, L; Casadesus, G; Kunos, G; Noy, N Fatty acid-binding protein 5 (FABP5) regulates cognitive function both by decreasing anandamide levels and by activating the nuclear receptor peroxisome proliferator-activated receptor ß/d (PPARß/d) in the brain. J Biol Chem 289:12748-58 (2014) [PubMed]  Article 
Target
Name:
Fatty acid-binding protein 5-ANS
Synonyms:
FABP5-ANS
Type:
Protein
Mol. Mass.:
n/a
Description:
n/a
Components:
This complex has 2 components.
Component 1
Name:
Fatty acid-binding protein 5
Synonyms:
FABP5_MOUSE | Fabp5 | Fabpe | Fatty acid-binding protein 5 (FABP5) | Klbp | Mal1
Type:
Protein
Mol. Mass.:
15137.27
Organism:
Mus musculus (Mouse)
Description:
Q05816
Residue:
135
Sequence:
MASLKDLEGKWRLMESHGFEEYMKELGVGLALRKMAAMAKPDCIITCDGNNITVKTESTVKTTVFSCNLGEKFDETTADGRKTETVCTFQDGALVQHQQWDGKESTITRKLKDGKMIVECVMNNATCTRVYEKVQ
  
Component 2
Name:
BDBM60927
Synonyms:
1-anilinonaphthalene-8-sulfonic acid | 8-Anilino-1-naphthalenesulfonic acid | ANS | Anilinonaphthalene-8-sulfonic acid (ANS) | BDBM50126831
Type:
n/a
Emp. Form.:
C16H13NO3S
Mol. Mass.:
299.344
SMILES:
OS(=O)(=O)c1cccc2cccc(Nc3ccccc3)c12
Structure:
Search PDB for entries with ligand similarity:
Inhibitor
Name:
BDBM22319
Synonyms:
(5Z,8Z,11Z,14Z)-icosa-5,8,11,14-tetraenoic acid | Arachidonic acid | Arachidonic acid (AA) | CHEMBL15594 | [1-14C]Arachidonic acid
Type:
Unsaturated fatty acid
Emp. Form.:
C20H32O2
Mol. Mass.:
304.4669
SMILES:
CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(O)=O
Structure:
Search PDB for entries with ligand similarity: