Reaction Details Report a problem with these data
Target
Melanocortin receptor 3
Ligand
BDBM230656
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
277.15±n/a K
IC50
1750±n/a nM
Comments
extracted
Citation
 Blaskovich, MA; Cassidy, PJ Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor US Patent  US9340517 Publication Date 5/17/2016 
Target
Name:
Melanocortin receptor 3
Synonyms:
MC3-R | MC3R | MC3R_HUMAN | Melanocortin MC3 | Melanocortin receptor (M3 and M4)
Type:
Enzyme
Mol. Mass.:
36044.86
Organism:
Homo sapiens (Human)
Description:
P41968
Residue:
323
Sequence:
MNASCCLPSVQPTLPNGSEHLQAPFFSNQSSSAFCEQVFIKPEVFLSLGIVSLLENILVILAVVRNGNLHSPMYFFLCSLAVADMLVSVSNALETIMIAIVHSDYLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTLIVAIWVCCGVCGVVFIVYSESKMVIVCLITMFFAMMLLMGTLYVHMFLFARLHVKRIAALPPADGVAPQQHSCMKGAVTITILLGVFIFCWAPFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILCGCNGMNLG
  
Inhibitor
Name:
BDBM230656
Synonyms:
US9340517, 105
Type:
Small organic molecule
Emp. Form.:
C35H40N6O2
Mol. Mass.:
576.7311
SMILES:
NC(=N)NCCC[C@H]1N[C@@H](CNC(=O)c2ccc3ccccc3c2)CCN(CC(c2ccccc2)c2ccccc2)C1=O
Structure:
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