Reaction Details Report a problem with these data
Target
Melanocortin receptor 5
Ligand
BDBM231717
Substrate
n/a
Meas. Tech.
Radioligand Binding Assay
pH
7.4±n/a
Temperature
310.15±n/a K
IC50
<10000±n/a nM
Comments
extracted
Citation
 Blaskovich, MA; Cassidy, PJ Methods of modulating the activity of the MC5 receptor and treatment of conditions related to this receptor US Patent  US9340517 Publication Date 5/17/2016 
Target
Name:
Melanocortin receptor 5
Synonyms:
MC-2 | MC5-R | MC5R | MC5R_HUMAN | Melanocortin MC5 | Melanocortin receptor (M4 and M5) | Melanocortin receptor 5 | Melanocortin receptor 5 (MC5R)
Type:
Enzyme
Mol. Mass.:
36612.92
Organism:
Homo sapiens (Human)
Description:
P33032
Residue:
325
Sequence:
MNSSFHLHFLDLNLNATEGNLSGPNVKNKSSPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHSPMYFFVCSLAVADMLVSMSSAWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALRYHHIMTARRSGAIIAGIWAFCTGCGIVFILYSESTYVILCLISMFFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVTMLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAFRSQEMRKTFKEIICCRGFRIACSFPRRD
  
Inhibitor
Name:
BDBM231717
Synonyms:
US9340517, 85
Type:
Small Organic Molecule
Emp. Form.:
C37H44N6O2
Mol. Mass.:
604.7843
SMILES:
CC(=O)NC(C[C@H]1CCN(CC(c2ccccc2)c2ccccc2)C(=O)[C@H](CCCNC(N)=N)N1)c1ccc2ccccc2c1
Structure:
Search PDB for entries with ligand similarity: